Malignant Mesothelioma, BAP1 Immunohistochemistry, and VEGFA: Does BAP1 Have Potential for Early Diagnosis and Assessment of Prognosis?

Malignant mesothelioma (MM) is an aggressive malignancy of the serosal membranes. Early diagnosis and accurate prognostication remain problematic. BAP1 is a tumour suppressor gene commonly mutated in MM. Germline BAP1 mutation has been associated with early onset and less aggressive disease compared...

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Bibliographic Details
Main Authors: Emily Pulford, Kalyani Huilgol, David Moffat, Douglas W. Henderson, Sonja Klebe
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2017/1310478