Methylation-associated silencing of BASP1 contributes to leukemogenesis in t(8;21) acute myeloid leukemia

Methylation-associated silencing of BASP1 contributes to leukemogenesis in t(8;21) acute myeloid leukemia

Cancer: Mismatched molecules unleash leukemia cell proliferation A chromosomal rearrangement commonly observed in certain leukemias selectively inactivates a gene that otherwise thwarts cancerous growth. Between 7 and 12% of acute myeloid leukemia cases exhibit a dramatic alteration in chromosomal s...

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Bibliographic Details
Main Authors: Lei Zhou, Lin Fu, Na Lv, Jing Liu, Yan Li, Xiaosu Chen, Qingyu Xu, Guofeng Chen, Baoxu Pang, Lili Wang, Yonghui Li, Xiaodong Zhang, Li Yu
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-018-0067-4

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https://doi.org/10.1038/s12276-018-0067-4

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