Immune responses to gp82 provide protection against mucosal Trypanosoma cruzi infection

The potential use of the Trypanosoma cruzi metacyclic trypomastigote (MT) stage-specific molecule glycoprotein-82 (gp82) as a vaccine target has not been fully explored. We show that the opsonization of T. cruzi MT with gp82-specific antibody prior to mucosal challenge significantly reduces parasite...

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Bibliographic Details
Main Authors: Christopher S Eickhoff, Olivia K Giddings, Nobuko Yoshida, Daniel F Hoft
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2010-08-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000500015