Neopterin is a cerebrospinal fluid marker for treatment outcome evaluation in patients affected by Trypanosoma brucei gambiense sleeping sickness.

BACKGROUND: Post-therapeutic follow-up is essential to confirm cure and to detect early treatment failures in patients affected by sleeping sickness (HAT). Current methods, based on finding of parasites in blood and cerebrospinal fluid (CSF) and counting of white blood cells (WBC) in CSF, are imperf...

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Main Authors: Natalia Tiberti, Veerle Lejon, Alexandre Hainard, Bertrand Courtioux, Xavier Robin, Natacha Turck, Krister Kristensson, Enock Matovu, John Charles Enyaru, Dieudonné Mumba Ngoyi, Sanjeev Krishna, Sylvie Bisser, Joseph Mathu Ndung'u, Philippe Büscher, Jean-Charles Sanchez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3585011?pdf=render