Differential pathways to adult metabolic dysfunction following poor nutrition at two critical developmental periods in sheep.

Epidemiological and experimental studies suggest early nutrition has long-term effects on susceptibility to obesity, cardiovascular and metabolic diseases. Small and large animal models confirm the influence of different windows of sensitivity, from fetal to early postnatal life, on offspring phenot...

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Bibliographic Details
Main Authors: Kirsten R Poore, Lisa J Hollis, Robert J S Murray, Anna Warlow, Andrew Brewin, Laurence Fulford, Jane K Cleal, Karen A Lillycrop, Graham C Burdge, Mark A Hanson, Lucy R Green
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3946277?pdf=render