Hypoxic Proliferation of Osteosarcoma Cells Depends on Arginase II

Background/Aims: Despite significant advancements in the diagnosis and treatment of osteosarcoma, the overall survival has remained relatively unchanged for over two decades. Hypoxic conditions have been demonstrated in solid tumors and are associated with increased cell proliferation and angiogenes...

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Bibliographic Details
Main Authors: Bhuvana A. Setty, Yi Jin, Peter J. Houghton, Nicholas D. Yeager, Thomas G. Gross, Leif D. Nelin
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:http://prod.karger.com/Article/FullText/447790