Lobeglitazone, a Novel Peroxisome Proliferator-Activated Receptor γ Agonist, Attenuates Renal Fibrosis Caused by Unilateral Ureteral Obstruction in Mice

Lobeglitazone, a Novel Peroxisome Proliferator-Activated Receptor γ Agonist, Attenuates Renal Fibrosis Caused by Unilateral Ureteral Obstruction in Mice

BackgroundRenal tubulointerstitial fibrosis is a common feature of the final stage of nearly all cause types of chronic kidney disease. Although classic peroxisome proliferator-activated receptor γ (PPARγ) agonists have a protective effect on diabetic nephropathy, much less is known about their dire...

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Main Authors: Kwi-Hyun Bae, Jung Beom Seo, Yun-A Jung, Hye-Young Seo, Sun Hee Kang, Hui-Jeon Jeon, Jae Man Lee, Sungwoo Lee, Jung-Guk Kim, In-Kyu Lee, Gwon-Soo Jung, Keun-Gyu Park
Format: Article
Language:English
Published: Academya Publishing Co. 2017-02-01
Series:Endocrinology and Metabolism
Subjects:
Renal tubulointerstitial fibrosis
Lobeglitazone
Transforming growth factor beta
Unilateral ureteral obstruction
Online Access:https://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-32-115.pdf

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https://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-32-115.pdf

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