Control of Persistent <i>Salmonella</i> Infection Relies on Constant Thymic Output Despite Increased Peripheral Antigen-Specific T Cell Immunity

Control of Persistent <i>Salmonella</i> Infection Relies on Constant Thymic Output Despite Increased Peripheral Antigen-Specific T Cell Immunity

Recent thymic emigrants are the youngest subset of peripheral T cells and their involvement in combating persistent bacterial infections has not been explored. Here, we hypothesized that CD4<sup>+</sup> recent thymic emigrants are essential immune mediators during persistent <i>Sal...

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Bibliographic Details
Main Authors: J. Alan Goggins, Jonathan R Kurtz, James B. McLachlan
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Pathogens
Subjects:
<i>Salmonella</i>
CD4<sup>+</sup> helper T cells
thymus
IL-17
persistent infection
recent thymic emigrants
Online Access:https://www.mdpi.com/2076-0817/9/8/605

Internet

https://www.mdpi.com/2076-0817/9/8/605

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