GFAP isoforms in adult mouse brain with a focus on neurogenic astrocytes and reactive astrogliosis in mouse models of Alzheimer disease.

Glial fibrillary acidic protein (GFAP) is the main astrocytic intermediate filament (IF). GFAP splice isoforms show differential expression patterns in the human brain. GFAPδ is preferentially expressed by neurogenic astrocytes in the subventricular zone (SVZ), whereas GFAP(+1) is found in a subset...

Full description

Bibliographic Details
Main Authors: Willem Kamphuis, Carlyn Mamber, Martina Moeton, Lieneke Kooijman, Jacqueline A Sluijs, Anne H P Jansen, Monique Verveer, Lody R de Groot, Vanessa D Smith, Sindhoo Rangarajan, José J Rodríguez, Marie Orre, Elly M Hol
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3418292?pdf=render