Estrogen Stimulation Differentially Impacts Human Male and Female Antigen-Specific T Cell Anti-Tumor Function and Polyfunctionality

Sex-specific differences exist in innate and adaptive immune responses and are mediated by hormone signaling. Estrogen is able to differentially modulate the development and differentiation of immune cells, including T cells. However, the effect of estrogen on T cell function, especially at concentr...

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Bibliographic Details
Main Authors: Flor C. Navarro BS, Stephanie K. Watkins PhD
Format: Article
Language:English
Published: SAGE Publishing 2017-12-01
Series:Gender and the Genome
Online Access:https://doi.org/10.1089/gg.2017.0014