Diesel exhaust particles induce cysteine oxidation and s-glutathionylation in house dust mite induced murine asthma.

Diesel exhaust particles induce cysteine oxidation and s-glutathionylation in house dust mite induced murine asthma.

Diesel exhaust particle (DEP) exposure enhances allergic inflammation and has been linked to the incidence of asthma. Oxidative stress on the thiol molecules cysteine (Cys) and glutathione (GSH) can promote inflammatory host responses. The effect of DEP on the thiol oxidation/reduction (redox) state...

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Bibliographic Details
Main Authors: Gerald B Lee, Eric B Brandt, Chang Xiao, Aaron M Gibson, Timothy D Le Cras, Lou Ann S Brown, Anne M Fitzpatrick, Gurjit K Khurana Hershey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3612047?pdf=render

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http://europepmc.org/articles/PMC3612047?pdf=render

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