The role of single N-glycans in proteolytic processing and cell surface transport of the Lassa virus glycoprotein GP-C

<p>Abstract</p> <p>Lassa virus glycoprotein is synthesised as a precursor (preGP-C) into the lumen of the endoplasmic reticulum. After cotranslational cleavage of the signal peptide, the immature GP-C is posttranslationally processed into the N-terminal subunit GP-1 and the C-termi...

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Bibliographic Details
Main Authors: Lenz Oliver, Eichler Robert, Garten Wolfgang, Strecker Thomas
Format: Article
Language:English
Published: BMC 2006-05-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/3/1/41