cAMP-Dependent Signaling Pathways as Potential Targets for Inhibition of Plasmodium falciparum Blood Stages

We review the role of signaling pathways in regulation of the key processes of merozoite egress and red blood cell invasion by Plasmodium falciparum and, in particular, the importance of the second messengers, cAMP and Ca2+, and cyclic nucleotide dependent kinases. cAMP-dependent protein kinase (PKA...

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Bibliographic Details
Main Authors: Edwin Lasonder, Kunal More, Shailja Singh, Malak Haidar, Daniela Bertinetti, Eileen J. Kennedy, Friedrich W. Herberg, Anthony A. Holder, Gordon Langsley, Chetan E. Chitnis
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Microbiology
Subjects:
PKA
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.684005/full