Topography of cancer-associated immune cells in human solid tumors

Lymphoid and myeloid cells are abundant in the tumor microenvironment, can be quantified by immunohistochemistry and shape the disease course of human solid tumors. Yet, there is no comprehensive understanding of spatial immune infiltration patterns (‘topography’) across cancer entities and across v...

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Bibliographic Details
Main Authors: Jakob Nikolas Kather, Meggy Suarez-Carmona, Pornpimol Charoentong, Cleo-Aron Weis, Daniela Hirsch, Peter Bankhead, Marcel Horning, Dyke Ferber, Ivan Kel, Esther Herpel, Sarah Schott, Inka Zörnig, Jochen Utikal, Alexander Marx, Timo Gaiser, Herrmann Brenner, Jenny Chang-Claude, Michael Hoffmeister, Dirk Jäger, Niels Halama
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/36967