The genomic architecture of EBV and infected gastric tissue from precursor lesions to carcinoma

The genomic architecture of EBV and infected gastric tissue from precursor lesions to carcinoma

Abstract Background Epstein-Barr virus (EBV)-associated gastric carcinomas (EBVaGCs) present unique molecular signatures, but the tumorigenesis of EBVaGCs and the role EBV plays during this process remain poorly understood. Methods We applied whole-exome sequencing, EBV genome sequencing, and whole-...

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Main Authors: Zhang-Hua Chen, Shu-Mei Yan, Xi-Xi Chen, Qi Zhang, Shang-Xin Liu, Yang Liu, Yi-Ling Luo, Chao Zhang, Miao Xu, Yi-Fan Zhao, Li-Yun Huang, Bin-Liu Liu, Tian-Liang Xia, Da-Zhi Xu, Yao Liang, Yong-Ming Chen, Wei Wang, Shu-Qiang Yuan, Hui-Zhong Zhang, Jing-Ping Yun, Wei-Wei Zhai, Mu-Sheng Zeng, Fan Bai, Qian Zhong
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Genome Medicine
Online Access:https://doi.org/10.1186/s13073-021-00963-2

Internet

https://doi.org/10.1186/s13073-021-00963-2

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