Cross-talk between mitochondria and proteasome in Parkinson's disease pathogenesis

Cross-talk between mitochondria and proteasome in Parkinson's disease pathogenesis

Parkinson’s disease (PD) is the most common progressive neurodegenerative movement disorder, characterized by the selective loss of nigrostriatal dopaminergic neurons, and the presence of intracellular insoluble proteinaceous inclusions, known as Lewy Bodies. Although PD etiopathogenesis r...

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Bibliographic Details
Main Authors: Diogo Martins Branco, Daniela M Arduino, A. Raquel Esteves, Diana F F Silva, Sandra M Cardoso, Catarina Oliveira
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
alpha-Synuclein
Dopamine
Mitochondria
Proteasome
Parkinson’s disease
substantia nigra pars compacta
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2010.00017/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2010.00017/full

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