Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF

Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF

This study assessed the potential for functional and anatomical recovery of the diseased aged primate nigrostriatal system, in response to trophic factor gene transfer. Aged rhesus monkeys received a single intracarotid infusion of MPTP, followed one week later by MRI-guided stereotaxic intrastriata...

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Bibliographic Details
Main Authors: M.E. Emborg, J. Moirano, J. Raschke, V. Bondarenko, R. Zufferey, S. Peng, A.D. Ebert, V. Joers, B. Roitberg, J.E. Holden, J. Koprich, J. Lipton, J.H. Kordower, P. Aebischer
Format: Article
Language:English
Published: Elsevier 2009-11-01
Series:Neurobiology of Disease
Subjects:
Macaque
MPTP
GDNF
Gene transfer
Parkinson's disease
Aging
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109002010

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http://www.sciencedirect.com/science/article/pii/S0969996109002010

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