O-GlcNAc as an Integrator of Signaling Pathways

O-GlcNAcylation is an important posttranslational modification governed by a single pair of enzymes–O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). These two enzymes mediate the dynamic cycling of O-GlcNAcylation on a wide variety of cytosolic, nuclear and mitochondrial proteins in a nutrient- and...

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Bibliographic Details
Main Authors: Qunxiang Ong, Weiping Han, Xiaoyong Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00599/full