Reconstruction of monocyte transcriptional regulatory network accompanies monocytic functions in human fibroblasts.

Reconstruction of monocyte transcriptional regulatory network accompanies monocytic functions in human fibroblasts.

Transcriptional regulatory networks (TRN) control the underlying mechanisms behind cellular functions and they are defined by a set of core transcription factors regulating cascades of peripheral genes. Here we report SPI1, CEBPA, MNDA and IRF8 as core transcription factors of monocyte TRN and demon...

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Bibliographic Details
Main Authors: Takahiro Suzuki, Mika Nakano-Ikegaya, Haruka Yabukami-Okuda, Michiel de Hoon, Jessica Severin, Satomi Saga-Hatano, Jay W Shin, Atsutaka Kubosaki, Christophe Simon, Yuki Hasegawa, Yoshihide Hayashizaki, Harukazu Suzuki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3302774?pdf=render

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http://europepmc.org/articles/PMC3302774?pdf=render

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