Cdan1 Is Essential for Primitive Erythropoiesis

Congenital dyserythropoietic anemia type I (CDA I) is an autosomal recessive disease characterized by moderate to severe macrocytic anemia and pathognomonic morphologic abnormalities of the erythroid precursors, including spongy heterochromatin. The disease is mainly caused by mutations in CDAN1 (en...

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Bibliographic Details
Main Authors: Sharon Noy-Lotan, Orly Dgany, Nathaly Marcoux, Ayelet Atkins, Gary M. Kupfer, Linette Bosques, Christine Gottschalk, Orna Steinberg-Shemer, Benny Motro, Hannah Tamary
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.685242/full