Locked Nucleic Acid Probe-Based Real-Time PCR Assay for the Rapid Detection of Rifampin-Resistant Mycobacterium tuberculosis.

Locked Nucleic Acid Probe-Based Real-Time PCR Assay for the Rapid Detection of Rifampin-Resistant Mycobacterium tuberculosis.

Drug-resistant Mycobacterium tuberculosis can be rapidly diagnosed through nucleic acid amplification techniques by analyzing the variations in the associated gene sequences. In the present study, a locked nucleic acid (LNA) probe-based real-time PCR assay was developed to identify the mutations in...

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Bibliographic Details
Main Authors: Yong Zhao, Guilian Li, Chongyun Sun, Chao Li, Xiaochen Wang, Haican Liu, Pingping Zhang, Xiuqin Zhao, Xinrui Wang, Yi Jiang, Ruifu Yang, Kanglin Wan, Lei Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0143444

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https://doi.org/10.1371/journal.pone.0143444

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