Natural and redesigned wasp venom peptides with selective antitumoral activity

Natural and redesigned wasp venom peptides with selective antitumoral activity

About 1 in 8 U.S. women (≈12%) will develop invasive breast cancer over the course of their lifetime. Surgery, chemotherapy, radiotherapy, and hormone manipulation constitute the major treatment options for breast cancer. Here, we show that both a natural antimicrobial peptide (AMP) derived from was...

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Bibliographic Details
Main Authors: Marcelo D. T. Torres, Gislaine P. Andrade, Roseli H. Sato, Cibele N. Pedron, Tania M. Manieri, Giselle Cerchiaro, Anderson O. Ribeiro, Cesar de la Fuente-Nunez, Vani X. Oliveira Jr.
Format: Article
Language:English
Published: Beilstein-Institut 2018-07-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
breast cancer
decoralin
MCF-7 cells
peptide design
selective anticancer peptides
structure–activity relationships
Online Access:https://doi.org/10.3762/bjoc.14.144

Internet

https://doi.org/10.3762/bjoc.14.144

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