Integrative Bioinformatics Approaches for Identification of Drug Targets in Hypertension

Integrative Bioinformatics Approaches for Identification of Drug Targets in Hypertension

High blood pressure or hypertension is an established risk factor for a myriad of cardiovascular diseases. Genome-wide association studies have successfully found over nine hundred loci that contribute to blood pressure. However, the mechanisms through which these loci contribute to disease are stil...

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Bibliographic Details
Main Authors: Daiane Hemerich, Jessica van Setten, Vinicius Tragante, Folkert W. Asselbergs
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
hypertension
blood pressure
epigenetic regulation
GWAS
data integration
functional annotation
Online Access:http://journal.frontiersin.org/article/10.3389/fcvm.2018.00025/full

Internet

http://journal.frontiersin.org/article/10.3389/fcvm.2018.00025/full

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