Effect of major tumor metabolites on release of doxorubicin from Doxil – implications for precision nano-medicine.
Our previous studies demonstrate that ammonia induces doxorubicin release from Doxil® in a concentration-dependent manner. Because ammonia that results from glutaminolysis is continu-ously generated in tumors at high enough concentration to induce doxorubicin release of Doxil in tumors, this may exp...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Andover House Inc.
2020-11-01
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| Series: | Precision Nanomedicine |
| Online Access: | http://prnano.scholasticahq.com/article/17956-effect-of-major-tumor-metabolites-on-release-of-doxorubicin-from-doxil-implications-for-precision-nano-medicine.pdf |