Polymorphism in Gag gene cleavage sites of HIV-1 non-B subtype and virological outcome of a first-line lopinavir/ritonavir single drug regimen.

Virological failure on a boosted-protease inhibitor (PI/r) first-line triple combination is usually not associated with the detection of resistance mutations in the protease gene. Thus, other resistance pathways are being investigated. First-line PI/r monotherapy is the best model to investigate in...

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Bibliographic Details
Main Authors: Jade Ghosn, Constance Delaugerre, Philippe Flandre, Julie Galimand, Isabelle Cohen-Codar, François Raffi, Jean-François Delfraissy, Christine Rouzioux, Marie-Laure Chaix
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3176769?pdf=render