Rubicon prevents autophagic degradation of GATA4 to promote Sertoli cell function.

Rubicon prevents autophagic degradation of GATA4 to promote Sertoli cell function.

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Autophagy degrades unnecessary proteins or damaged organelles to maintain cellular function. Therefore, autophagy has a preventive role against various diseases including hepatic disorders, neurodegenerative diseases, and cancer. Although autophagy in germ cells or Sertoli cells is known to be requi...

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Bibliographic Details
Main Authors: Tadashi Yamamuro, Shuhei Nakamura, Yu Yamano, Tsutomu Endo, Kyosuke Yanagawa, Ayaka Tokumura, Takafumi Matsumura, Kiyonori Kobayashi, Hideto Mori, Yusuke Enokidani, Gota Yoshida, Hitomi Imoto, Tsuyoshi Kawabata, Maho Hamasaki, Akiko Kuma, Sohei Kuribayashi, Kentaro Takezawa, Yuki Okada, Manabu Ozawa, Shinichiro Fukuhara, Takashi Shinohara, Masahito Ikawa, Tamotsu Yoshimori
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-08-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009688

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https://doi.org/10.1371/journal.pgen.1009688

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