Regulation of Interferon-γ receptor (IFN-γR) expression in macrophages during Mycobacterium tuberculosis infection
Interferon-gamma (IFN-γ) is a key cytokine that mediates immunity to tuberculosis (TB). Mycobacterium tuberculosis (M. tb) is known to downregulate the surface expression of IFN-γ receptor (IFN-γR) on macrophages and peripheral blood mononuclear cells (PBMCs) of patients with active TB disease. Many...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2020-04-01
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Series: | Biomolecular Concepts |
Subjects: | |
Online Access: | https://doi.org/10.1515/bmc-2020-0006 |