Low sulfide levels and a high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) in the long-lived naked mole-rat

Low sulfide levels and a high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) in the long-lived naked mole-rat

Hydrogen sulfide (H2S) is a gaseous signalling molecule involved in many physiological and pathological processes. There is increasing evidence that H2S is implicated in aging and lifespan control in the diet-induced longevity models. However, blood sulfide concentration of naturally long-lived spec...

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Bibliographic Details
Main Authors: Maja Dziegelewska, Susanne Holtze, Christiane Vole, Ulrich Wachter, Uwe Menzel, Michaela Morhart, Marco Groth, Karol Szafranski, Arne Sahm, Christoph Sponholz, Philip Dammann, Klaus Huse, Thomas Hildebrandt, Matthias Platzer
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Redox Biology
Subjects:
Transsulfuration
Hydrogen sulfide
Methionine
Longevity
Mole-rats
Low methionine diet
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231716300088

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http://www.sciencedirect.com/science/article/pii/S2213231716300088

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