Change point analyses in prodromal Alzheimer’s disease

Change point analysis can reveal when a biomarker starts to diverge from the pattern of normal aging. This paper analyzes several biomarkers from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) to estimate the sequence and timing of their change points relative to a subsequent clinical diagno...

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Bibliographic Details
Main Authors: Alvin H. Bachman, Babak A. Ardekani
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Biomarkers in Neuropsychiatry
Subjects:
MCI
Online Access:http://www.sciencedirect.com/science/article/pii/S2666144620300186