Mechanisms of the scaffold subunit in facilitating protein phosphatase 2A methylation.

The function of the biologically essential protein phosphatase 2A (PP2A) relies on formation of diverse heterotrimeric holoenzymes, which involves stable association between PP2A scaffold (A) and catalytic (C or PP2Ac) subunits and binding of variable regulatory subunits. Holoenzyme assembly is high...

Full description

Bibliographic Details
Main Authors: Vitali Stanevich, Aiping Zheng, Feng Guo, Li Jiang, Nathan Wlodarchak, Yongna Xing
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3900686?pdf=render