Disruption of the astrocyte–neuron interaction is responsible for the impairments in learning and memory in 5XFAD mice: an Alzheimer’s disease animal model

Disruption of the astrocyte–neuron interaction is responsible for the impairments in learning and memory in 5XFAD mice: an Alzheimer’s disease animal model

Abstract The morphological dynamics of astrocytes are altered in the hippocampus during memory induction. Astrocyte–neuron interactions on synapses are called tripartite synapses. These control the synaptic function in the central nervous system. Astrocytes are activated in a reactive state by STAT3...

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Bibliographic Details
Main Authors: Moonseok Choi, Sang-Min Lee, Dongsoo Kim, Heh-In Im, Hye-Sun Kim, Yun Ha Jeong
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Molecular Brain
Subjects:
Astrocyte–neuron interaction
Learning impairments
Memory impairments
Alzheimer’s disease
5XFAD mice
Online Access:https://doi.org/10.1186/s13041-021-00823-5

Internet

https://doi.org/10.1186/s13041-021-00823-5

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