FGF8 morphogen gradients are differentially regulated by heparan sulphotransferases Hs2st and Hs6st1 in the developing brain

Fibroblast growth factor (FGF) morphogen signalling through the evolutionarily ancient extracellular signalling-regulated kinase/mitogen activated protein kinase (ERK/MAPK) pathway recurs in many neural and non-neural developmental contexts, and understanding the mechanisms that regulate FGF/ERK fun...

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Bibliographic Details
Main Authors: Wai-Kit Chan, David J. Price, Thomas Pratt
Format: Article
Language:English
Published: The Company of Biologists 2017-12-01
Series:Biology Open
Subjects:
Erk
Online Access:http://bio.biologists.org/content/6/12/1933