Association analysis of canonical Wnt signalling genes in diabetic nephropathy.

Several studies have provided compelling evidence implicating the Wnt signalling pathway in the pathogenesis of diabetic nephropathy. Gene expression profiles associated with renal fibrosis have been attenuated through Wnt pathway modulation in model systems implicating Wnt pathway members as potent...

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Bibliographic Details
Main Authors: David H Kavanagh, David A Savage, Christopher C Patterson, Amy Jayne McKnight, John K Crean, Alexander P Maxwell, Gareth J McKay, Warren 3/UK GoKinD Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3158097?pdf=render