Novel role of ER stress and autophagy in Microcystin-LR induced apoptosis in Chinese hamster ovary cells

Microcystin-LR (MC-LR) is a ubiquitous peptide that exhibits strong reproductive toxicity, although the mechanistic basis for such toxicity remains largely unknown. The present study was conducted to investigate the mechanisms underlying the adverse effects of exposure to MC-LR in Chinese hamster ov...

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Bibliographic Details
Main Authors: Shenshen Zhang, Chuanrui Liu, Yang Li, Mustapha Umar Imam, Hui Huang, Haohao Liu, Yongjuan Xin, Huizhen Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00527/full