A prospective pilot study using metabolomics discloses specific fatty acid, catecholamine and tryptophan metabolic pathways as possible predictors for a negative outcome after severe trauma

A prospective pilot study using metabolomics discloses specific fatty acid, catecholamine and tryptophan metabolic pathways as possible predictors for a negative outcome after severe trauma

Abstract Background We wanted to define metabolomic patterns in plasma to predict a negative outcome in severe trauma patients. Methods A prospective pilot study was designed to evaluate plasma metabolomic patterns, established by liquid chromatography coupled to mass spectrometry, in patients alloc...

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Bibliographic Details
Main Authors: Luis Servià, Mariona Jové, Joaquim Sol, Reinald Pamplona, Mariona Badia, Neus Montserrat, Manuel Portero-Otin, Javier Trujillano
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Subjects:
Metabolome
Mortality
Traumatic brain injury
Biomarker
Multiple traumatism
Online Access:http://link.springer.com/article/10.1186/s13049-019-0631-5

Internet

http://link.springer.com/article/10.1186/s13049-019-0631-5

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