Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites

Current strategies for regulatory control of gene expression are orthogonal to the host organism mechanisms. Here the authors demonstrate an RNA aptamer controlled system integrated into native regulatory pathways in the parasite Plasmodium falciparum.

Bibliographic Details
Main Authors: Suresh M. Ganesan, Alejandra Falla, Stephen J. Goldfless, Armiyaw S. Nasamu, Jacquin C. Niles
Format: Article
Language:English
Published: Nature Publishing Group 2016-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10727