Circadian clocks in mouse and human CD4+ T cells.

Though it has been shown that immunological functions of CD4+ T cells are time of day-dependent, the underlying molecular mechanisms remain largely obscure. To address the question whether T cells themselves harbor a functional clock driving circadian rhythms of immune function, we analyzed clock ge...

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Bibliographic Details
Main Authors: Thomas Bollinger, Anton Leutz, Alexei Leliavski, Ludmila Skrum, Judit Kovac, Luigi Bonacina, Christian Benedict, Tanja Lange, Jürgen Westermann, Henrik Oster, Werner Solbach
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3247291?pdf=render