Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia

Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia

Mitochondria use oxygen as the final acceptor of the respiratory chain, but its incomplete reduction can also produce reactive oxygen species (ROS), especially superoxide. Acute hypoxia produces a superoxide burst in different cell types, but the triggering mechanism is still unknown. Herein, we sho...

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Bibliographic Details
Main Authors: Pablo Hernansanz-Agustín, Elena Ramos, Elisa Navarro, Esther Parada, Nuria Sánchez-López, Laura Peláez-Aguado, J. Daniel Cabrera-García, Daniel Tello, Izaskun Buendia, Anabel Marina, Javier Egea, Manuela G. López, Anna Bogdanova, Antonio Martínez-Ruiz
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717301271

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http://www.sciencedirect.com/science/article/pii/S2213231717301271

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