Increased thiol levels in antimony-resistant Leishmania infantum isolated from treatment-refractory visceral leishmaniasis in Brazil

Increased thiol levels in antimony-resistant Leishmania infantum isolated from treatment-refractory visceral leishmaniasis in Brazil

BACKGROUND Treatment-refractory visceral leishmaniasis (VL) has become an important problem in many countries. OBJECTIVES We evaluated the antimony-resistance mechanisms of Leishmania infantum isolated from VL patients refractory or responsive to treatment with pentavalent antimony. METHODS Strain...

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Bibliographic Details
Main Authors: Lucas S Magalhães, Lays GS Bomfim, Sthefanne G Mota, Geydson S Cruz, Cristiane B Corrêa, Diego M Tanajura, Michael W Lipscomb, Valéria M Borges, Amélia R de Jesus, Roque P de Almeida, Tatiana R de Moura
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Leishmania
visceral leishmaniasis
antimony
drug resistance
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762018000200119&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762018000200119&lng=en&tlng=en

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