Fibroblast Growth Factor Receptors (FGFRs): Structures and Small Molecule Inhibitors

Fibroblast growth factor receptors (FGFRs) are a family of receptor tyrosine kinases expressed on the cell membrane that play crucial roles in both developmental and adult cells. Dysregulation of FGFRs has been implicated in a wide variety of cancers, such as urothelial carcinoma, hepatocellular car...

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Bibliographic Details
Main Authors: Shuyan Dai, Zhan Zhou, Zhuchu Chen, Guangyu Xu, Yongheng Chen
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/6/614