Improvement of cardiac function in mouse myocardial infarction after transplantation of epigenetically-modified bone marrow progenitor cells.

To study usefulness of bone marrow progenitor cells (BPCs) epigenetically altered by chromatin modifying agents in mediating heart repair after myocardial infarction in mice.We tested the therapeutic efficacy of bone marrow progenitor cells treated with the clinically-used chromatin modifying agents...

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Bibliographic Details
Main Authors: Johnson Rajasingh, Jayakumar Thangavel, Mohammad R Siddiqui, Ignatius Gomes, Xiao-pei Gao, Raj Kishore, Asrar B Malik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3142193?pdf=render