Antivirals for allosteric inhibition of Zika virus using a homology model and experimentally determined structure of envelope protein

Abstract Objective An approach to inhibiting enveloped flaviviruses is to deter the ability of the envelope protein(s) binding onto glycoproteins. In previous work, using a small ~100-amino acid homology model of Zika virus envelope protein (ZVEP), we proved the susceptibility of Zika virus to inhib...

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Bibliographic Details
Main Authors: Sandun Fernando, Teshan Fernando
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Research Notes
Online Access:http://link.springer.com/article/10.1186/s13104-017-2685-7