Epac1 inhibits PKR to reduce NLRP3 inflammasome proteins in retinal endothelial cells

Youde Jiang, Jena J SteinleDepartment of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, Detroit, MI, USAPurpose: Inflammation has been strongly associated with retinal damage in diseases such as diabetic retinopathy. Several studies have reported that high...

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Bibliographic Details
Main Authors: Jiang Y, Steinle JJ
Format: Article
Language:English
Published: Dove Medical Press 2019-06-01
Series:Journal of Inflammation Research
Subjects:
PKR
Online Access:https://www.dovepress.com/epac1-inhibits-pkr-to-reduce-nlrp3-inflammasome-proteins-in-retinal-en-peer-reviewed-article-JIR