Loss of the neurodevelopmental gene Zswim6 alters striatal morphology and motor regulation

Loss of the neurodevelopmental gene Zswim6 alters striatal morphology and motor regulation

The zinc-finger SWIM domain-containing protein 6 (ZSWIM6) is a protein of unknown function that has been associated with schizophrenia and limited educational attainment by three independent genome-wide association studies. Additionally, a putatively causal point mutation in ZSWIM6 has been identifi...

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Bibliographic Details
Main Authors: David J. Tischfield, Dave K. Saraswat, Andrew Furash, Stephen C. Fowler, Marc V. Fuccillo, Stewart A. Anderson
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Neurobiology of Disease
Subjects:
ZSWIM6
Striatum
Schizophrenia
Medium spiny neurons
Hyperactivity
Motor behavior
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996117300876

Internet

http://www.sciencedirect.com/science/article/pii/S0969996117300876

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