Parallel Colorimetric Quantification of Choline and Phosphocholine as a Method for Studying Choline Kinase Activity in Complex Mixtures

Choline kinase (Chok) is an enzyme found in eukaryotes and Gram-positive bacteria. Chok catalyzes the production of phosphocholine from choline and ATP. This enzyme has been validated as a drug target in Streptococcus pneumonia, but the role Chok enzymatic activity plays in bacterial cell growth and...

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Bibliographic Details
Main Authors: Tahl Zimmerman, Salam A. Ibrahim
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Antibiotics
Subjects:
Online Access:http://www.mdpi.com/2079-6382/7/1/24