Cellular and Animal Models of Striated Muscle Laminopathies

The lamin A/C (<i>LMNA</i>) gene codes for nuclear intermediate filaments constitutive of the nuclear lamina. <i>LMNA</i> has 12 exons and alternative splicing of exon 10 results in two major isoforms&#8212;lamins A and C. Mutations found throughout the <i>LMNA</...

Full description

Bibliographic Details
Main Authors: Hannah A. Nicolas, Marie-Andrée Akimenko, Frédérique Tesson
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cells
Subjects:
DCM
Online Access:https://www.mdpi.com/2073-4409/8/4/291