Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport

Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport

PACSIN proteins are known to mediate membrane tubulation. Here the authors show that PACSIN - positive membranous tubules extend from the ciliary pocket membrane and during ciliogenesis from the ciliary vesicle to the plasma membrane, called extracellular membrane channels (EMCs).

Bibliographic Details
Main Authors: Christine Insinna, Quanlong Lu, Isabella Teixeira, Adam Harned, Elizabeth M. Semler, Jim Stauffer, Valentin Magidson, Ajit Tiwari, Anne K. Kenworthy, Kedar Narayan, Christopher J. Westlake
Format: Article
Language:English
Published: Nature Publishing Group 2019-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-08192-9

Internet

https://doi.org/10.1038/s41467-018-08192-9

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