The Labile Iron Pool Reacts Rapidly and Catalytically with Peroxynitrite

While investigating peroxynitrite-dependent oxidation in murine RAW 264.7 macrophage cells, we observed that removal of the Labile Iron Pool (LIP) by chelation increases the intracellular oxidation of the fluorescent indicator H<sub>2</sub>DCF, so we concluded that the LIP reacts with pe...

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Bibliographic Details
Main Authors: André Luís Condeles, José Carlos Toledo Junior
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/11/9/1331