Origin of the Phosphoprotein Phosphatase (PPP) sequence family in Bacteria: Critical ancestral sequence changes, radiation patterns and substrate binding features

Origin of the Phosphoprotein Phosphatase (PPP) sequence family in Bacteria: Critical ancestral sequence changes, radiation patterns and substrate binding features

Background: Phosphoprotein phosphatases (PPP) belong to the PPP Sequence family, which in turn belongs to the broader metallophosphoesterase (MPE) superfamily. The relationship between the PPP Sequence family and other members of the MPE superfamily remains unresolved, in particular what transitions...

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Bibliographic Details
Main Authors: David Kerk, Mario E. Valdés-Tresanco, Ryan Toth, Sergei Yu. Noskov, Kenneth K.-S. Ng, Greg B. Moorhead
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:BBA Advances
Subjects:
Protein phosphatase
Metallophosphoesterase
Phylogenetic analysis
Molecular dynamics simulation
Bacterial origin
Phosphomonoesterase
Online Access:http://www.sciencedirect.com/science/article/pii/S2667160321000041

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http://www.sciencedirect.com/science/article/pii/S2667160321000041

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