Protein Biomarkers for Early Detection of Pancreatic Ductal Adenocarcinoma: Progress and Challenges

Protein Biomarkers for Early Detection of Pancreatic Ductal Adenocarcinoma: Progress and Challenges

Approximately 75% of patients with pancreatic ductal adenocarcinoma are diagnosed with advanced cancer, which cannot be safely resected. The most commonly used biomarker CA19-9 has inadequate sensitivity and specificity for early detection, which we define as Stage I/II cancers. Therefore, progress...

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Bibliographic Details
Main Authors: Alex Root, Peter Allen, Paul Tempst, Kenneth Yu
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Cancers
Subjects:
pancreatic ductal adenocarcinoma
early detection
biomarkers
blood test
ELISA
mass spectrometry
circulating DNA
thrombospondin
CA19-9
KRAS
Online Access:http://www.mdpi.com/2072-6694/10/3/67

Internet

http://www.mdpi.com/2072-6694/10/3/67

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